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CYTOCHALASIN C |
| Synonyms. Cytochalasin C; (3S-(3R*,3aS*,6R*,6aS*,7E,10R*,12S*,13E,15S*,15aS*))-15-(Acetyloxy)-3,3a,6,6a, 9,10,12,15- octahydro- 6,12-dihydroxy-4,5,10,12-tetramethyl-3-(phenylmethyl)-1H-cycloundec(d)isoindole- 1,11(2H)-dione; 7(S),18-Dihydroxy-16(S),18(R)-dimethyl-10-phenyl(11)cytochalasa-5,13(E),19(E)-triene-1,17-dione 21(R)-acetate; |
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| PRODUCT IDENTIFICATION | |
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CAS RN |
22144-76-9 |
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EINECS RN |
244-803-6 |
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FORMULA |
C30H37NO6 |
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MOLE WEIGHT |
507.62 |
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H.S CODE |
2933.79.0800 |
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SMILES |
N1[C@@H]([C@@H]2C(=C([C@H]([C@H]3[C@]2(C1=O)[C@@H](C=C[ C@@] (C([C@H](CC=C3)C) =O)(C)O)OC(=O)C)O)C)C)Cc1ccccc1 |
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CLASSIFICATION |
Mycotoxin, Actin inhibitor |
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EXTRA NOTES |
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| PHYSICAL AND CHEMICAL PROPERTIES | |
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PHYSICAL STATE. |
white powder |
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MELTING POINT |
2 ~ C |
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BOILING POINT |
2 ~ C |
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DENSITY |
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SOLUBILITY IN WATER |
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| SOLVENT SOLUBILITY |
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VAPOR DENSITY |
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log P(octanol-water) |
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VAPOR PRESSURE |
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AUTOIGNITION TEMP |
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| pK |
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REFRACTIVE INDEX |
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FLASH POINT |
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| STABILITY AND REACTIVITY | |
| STABILITY | Stable under normal conditions. |
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INCOMPATIBLE MATERIALS |
Strong oxidizing agents |
| POLYMERIZATION |
Has not been reported |
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NFPA RATINGS |
Health: 1, Flammability: 0, Reactivity: 0 |
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| EXTERNAL LINKS & GENERAL DESCRIPTION |
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USA.gov - Cytochalasin C Wikipedia Linking - Cytochalasin Google Scholar Search - Cytochalasin C U.S. National Library of Medicine - Cytochalasin C PubChem Compound Summary - Cytochalasin C KEGG (Kyoto Encyclopedia of Genes and Genomes) - Cytochalasin C NCBI (http://www.ncbi.nlm.nih.gov/) - Cytochalasin C Cytochalasin A is a metabolite of the fungus Drechslera (previously Heiminthosporium) dematioideum. Cytochalasin A is sulfhydryl-reactive, and was shown to inhibit growth and sugar uptake in a Saccharomyces strain. Unlike Cytochalasin B, Cytochalasin C and Cytochalasin D are isomeric metabolites of Metarrhizium anisopliae. Cytochalasin D possesses antibiotic and antitumor activity. It also impairs maintenance of long term potentiation (LTP) of actin filaments. It is implicated in promoting conditions favorable for depolymerizing actin. sigmaaldrich |
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| SALES SPECIFICATION | |
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APPEARANCE |
white powder |
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ASSAY |
98% min |
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| TRANSPORT & REGULATORY INFORMATION | |
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UN NO. |
1544 |
| HAZARD CLASS |
6.1 |
| PACKING GROUP | II |
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| SAFETY INFORMATION | |
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HAZARD OVERVIEW |
GHS (Globally Harmonised System) Classification: Acute toxicity (Oral). Acute toxicity (Inhalation). Acute toxicity (Dermal). Reproductive toxicity. Hazard statements: Fatal if swallowed or in contact with skin. Fatal if inhaled. Suspected of damaging fertility or the unborn child. |
| SIGNAL WORD | Danger |
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PICTOGRAMS |
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HAZARD STATEMENTS |
H300 + H310-H330-H361 |
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P STATEMENTS |
P260-P264-P280-P284-P302 + P350-P310 |
| EC DIRECTIVES |
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| HAZARD CODES |
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RISK PHRASES |
63-26/27/28 |
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SAFETY PHRASES |
28-36/37-45 |
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| PACKING |
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Preserve in light-resistant and well-closed containers |
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